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Search Results for " alzheimer disease "

20

Compounds

Cat No. Product Name Synonyms Targets
TP1856 Colivelin Beta Amyloid , STAT
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
T7891 Ipidacrine NIK‐247 Others
Ipidacrine (NIK‐247) (NIK‐247) is an Antidementia Agent
T14199 ALZ-801 Valiltramiprosate Beta Amyloid
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-m...
T16481 PF-04995274 5-HT Receptor
PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has a...
T6483 EHT 1864 EHT 1864 2HCl Rho , Ras
EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).
T1993 J-147 J147 Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T9611 PF-04802367 GSK-3
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and ...
T5678 Lazabemide hydrochloride N-(2-Aminoethyl)-5-chlor-2-pyridincarbox MAO , Monoamine Oxidase
Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki:7.9nM).
T5470 LAZABEMIDE Ro 19-6327 MAO , Monoamine Oxidase
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T12525 Pozanicline dihydrochloride ABT-089 dihydrochloride AChR
Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)
T31645 EO-1606 EO1606,EO 1606 p38 MAPK
EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.
T37089 Iclepertin BI-425809 GlyT
Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin...
T20172L Kyotorphin acetate Endogenous Metabolite , Antibacterial
Kyotorphin acetate is an endogenous peptide with analgesia activity and can be used as a biomarker of Alzheimer disease.
T4955 Saponaretin Isovitexin,Apigenin-6-C-glucoside Apoptosis , Antioxidant
saponaretin, an active component of many traditional Chinese medicines, shows various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.
T8448 ZSET1446 ZSET-1446,ST-101 Calcium Channel , AChR
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
T84293 SSR 180 SSR180711 AChR
SSR 180 is a potent and subtype-selective α7 agonist with applications in the study of Alzheimer;s disease and schizophrenia.
T3782 Jujuboside A transporter , GABA Receptor
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, having neurophysiological inhibitory effects, used as a potential therapeutic agent for the treatment of Alzheimer s disease.
TN1140 Onjisaponin B AMPK , mTOR , Autophagy
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parki...
T1628 Rivastigmine tartrate SDZ-ENA 713,ENA 713 AChR , AChE
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON...
T0229 Rivastigmine SDZ-ENA 713,S-Rivastigmine,Exelon AChE
Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
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TargetMol