20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1856 | Colivelin | Beta Amyloid , STAT | |
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). | |||
T7891 | Ipidacrine | NIK‐247 | Others |
Ipidacrine (NIK‐247) (NIK‐247) is an Antidementia Agent | |||
T14199 | ALZ-801 | Valiltramiprosate | Beta Amyloid |
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-m... | |||
T16481 | PF-04995274 | 5-HT Receptor | |
PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has a... | |||
T6483 | EHT 1864 | EHT 1864 2HCl | Rho , Ras |
EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM). | |||
T1993 | J-147 | J147 | Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase |
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate... | |||
T9611 | PF-04802367 | GSK-3 | |
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and ... | |||
T5678 | Lazabemide hydrochloride | N-(2-Aminoethyl)-5-chlor-2-pyridincarbox | MAO , Monoamine Oxidase |
Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki:7.9nM). | |||
T5470 | LAZABEMIDE | Ro 19-6327 | MAO , Monoamine Oxidase |
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). | |||
T12525 | Pozanicline dihydrochloride | ABT-089 dihydrochloride | AChR |
Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM) | |||
T31645 | EO-1606 | EO1606,EO 1606 | p38 MAPK |
EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis. | |||
T37089 | Iclepertin | BI-425809 | GlyT |
Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin... | |||
T20172L | Kyotorphin acetate | Endogenous Metabolite , Antibacterial | |
Kyotorphin acetate is an endogenous peptide with analgesia activity and can be used as a biomarker of Alzheimer disease. | |||
T4955 | Saponaretin | Isovitexin,Apigenin-6-C-glucoside | Apoptosis , Antioxidant |
saponaretin, an active component of many traditional Chinese medicines, shows various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on. | |||
T8448 | ZSET1446 | ZSET-1446,ST-101 | Calcium Channel , AChR |
ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models. | |||
T84293 | SSR 180 | SSR180711 | AChR |
SSR 180 is a potent and subtype-selective α7 agonist with applications in the study of Alzheimer;s disease and schizophrenia. | |||
T3782 | Jujuboside A | transporter , GABA Receptor | |
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, having neurophysiological inhibitory effects, used as a potential therapeutic agent for the treatment of Alzheimer s disease. | |||
TN1140 | Onjisaponin B | AMPK , mTOR , Autophagy | |
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parki... | |||
T1628 | Rivastigmine tartrate | SDZ-ENA 713,ENA 713 | AChR , AChE |
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON... | |||
T0229 | Rivastigmine | SDZ-ENA 713,S-Rivastigmine,Exelon | AChE |
Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease. |